煤烟型大气污染对儿童免疫功能的影响

Effect of coal-burning air pollution on children immune function

为了研究煤烟型大气污染对儿童免疫功能的影响 ,在煤烟型大气污染城市太原市的三个污染水平不同的研究区选取居住 3年以上 4 - 5年级的小学生测试T淋巴细胞亚群分类 (CD3+、CD4+、CD8+)、唾液溶菌酶含量和免疫球蛋白含量。结果发现小学生的唾液溶菌酶含量和免疫球蛋白 (IgG、IgA、IgM)均低于对照区 ,且有显著性差异 (P <0 .0 5) ;T淋巴细胞亚群分类 (CD3+、CD4+、CD8+百分含量 )有同样的趋势 ,但差异不显著 (P >0 0 5)。结果表明太原市煤烟型大气污染对小学生的非特异性免疫、体液免疫产生一定的影响 。

Study of effect of coal burning air pollution on children immunity function was hold in Taiyuan city which is one of typical coal burning air pollution city in China. The children of grade 4-5 who dwell more than 3 years were screened in three different pollution areas. The test includes the observation on the T lymphocyte subpopulations classes (CD3 +,CD4 +and CD8 +) , saliva lysozyme contents and immunoglobulin content. The results showed that the contents of saliva lysozyme and immunoglobulin were lower than those in control area respectively( P <0.05), and T lymphocyte subpopulations class (the percent ages of CD3 +,CD4 +and CD8 +)had the same trend, but it was not marked. The results suggested that coal-burning air pollution could affect children by nonspecific immunity and sap immunity. The effect on cell immunity was not marked.