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Rapid Gas Chromatographic Assay of Diazinon:Application to the Study of Diazinon Kinetics in Rats

Rapid Gas Chromatographic Assay of Diazinon:Application to the Study of Diazinon Kinetics in Rats
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摘要 A rapid method was developed for the determination of diazinon in plasma using gas chromatography with electron-capture detection (GC-ECD). Following a single extraction with hexane from 100μl of plasma, diazinon was quantitated on a 3% OV-17 column. The detection limit was 10 ng/ml and linearity was obtained in the range of 25 ng/ml-2500 ng/ml.The applicability of the assay to single-dose kinetics in rats is illustrated A rapid method was developed for the determination of diazinon in plasma using gas chromatography with electron-capture detection (GC-ECD). Following a single extraction with hexane from 100μl of plasma, diazinon was quantitated on a 3% OV-17 column. The detection limit was 10 ng/ml and linearity was obtained in the range of 25 ng/ml-2500 ng/ml.The applicability of the assay to single-dose kinetics in rats is illustrated
出处 《Biomedical and Environmental Sciences》 SCIE CAS CSCD 1994年第4期357-361,共5页 生物医学与环境科学(英文版)
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