复发性尿路感染致病菌及耐药性研究

Study on pathogenic bacteria and drug resistance of recurrent urinary tract infection

目的检测复发性尿路感染致病菌种类并对其耐药性进行研究。方法选取2017年12月至2019年2月复发性尿路感染患者64例,以患者中段尿为样本,通过血琼脂平板培养菌种进行药敏实验,研究不同致病菌对不同抗菌药的耐药性。结果患者尿液样本中,革兰阴性致病菌占主要部分,占比为69.35%,以大肠埃希菌为主。革兰阴性致病菌对氨苄西林耐药性最高,对阿米卡星、亚胺培南敏感性最强;革兰阳性致病菌对氨苄西林耐药性最高,对替考拉宁敏感性最强。结论临床治疗中,应结合细菌检测和药敏实验结果进行合理用药。

Objective To detect the pathogens of recurrent urinary tract infection and study its drug resistance.Methods Sixty-four patients with recurrent urinary tract infections from December 2017 to February 2019 were selected.The patient’s mid-stage urine was used as a sample,and the drug sensitivity test was carried out on the blood agar plate culture strain to study the resistance of different pathogenic bacteria to different antibacterial drugs.Results In the urine samples of patients,Gram-negative pathogenic bacteria accounted for the majority,accounting for 69.35%,mainly Escherichia coli.Gram-negative pathogens had the highest resistance to ampicillin and the strongest sensitivity to amikacin and imipenem;Gram-positive pathogens had the highest resistance to ampicillin and sensitivity to teicoplanin.Conclusions In clinical treatment,rational use of drugs should be combined with the results of bacterial testing and drug susceptibility testing.