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环氧化酶-2和血管内皮生长因子C表达与喉癌淋巴管转移 被引量：1

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摘要 环氧化酶-2(cyclooxygenase-2,COX-2)是前列腺素合成的关键酶,在头颈鳞状细胞癌(简称鳞癌)等多种恶性肿瘤中表达上调,并与肿瘤发生和发展有关。淋巴管转移是喉鳞癌最常见的转移方式,血管内皮生长因子C(vascular endothelial growth factor C,VEGF-C)
作者 曾泉 胡国华 谢亚柳
机构地区 重庆医科大学第一附属医院耳鼻咽喉科
出处 《中国耳鼻咽喉头颈外科》 北大核心 2008年第7期430-431,共2页 Chinese Archives of Otolaryngology-Head and Neck Surgery
关键词 喉肿瘤(Laryngeal Neoplasms) 环氧化酶2(Cyclooxygenase 2) 血管内皮生长因子C(Vascular ENDOTHELIAL Growth Factor C) 肿瘤转
分类号 R739.65 [医药卫生—肿瘤]
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参考文献5

  • 1王中亮,陈尧,周斌,梁传余,张林,李瑞祥.血管内皮生长因子C在喉鳞癌中的表达[J].四川大学学报（医学版）,2004,35(1):47-49. 被引量：3
  • 2Al -Rawi MA,Mansel RE,Jiang WG.Lymphangiogenesis and its role in cancer[].Histology and Histopathology.2005
  • 3Su J L,Shih J Y,Yen M L, et al.Cyclooxygenase-2 induces EP1-and HER-2/Neu-dependent vascular endothelial growth factor-C up-regulation: a novel mechanism of lymphangiogenesis in lung adenocarcinoma[].Cancer Research.2004
  • 4Kyzas P A,Stefanou D,Agnantis N J.COX-2 expression correlates with VEGF-C and lymph node metastases in patients with head and neck squamous cell carcinoma[].Modern Pathology.2005
  • 5Kari A,Suresh M,Erkki R.Lymphangiogenesis and cancer[].Cancer Research.2004

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同被引文献12

  • 1Tanaka T,Suzuki R, Kohno H,et al.Colonie adenoearcino- mas rapidly induced by the combined treatment with 2- amino-1-methyl-6-phenylimidazo[4,5-b]pyridine and dex- tran sodium sulfate in male ICR mice possess beta-eatenin gene mutations and increases immunoreaetivity for beta- eatenin,eyelooxygenase-2 and inducible nitric oxide syn- thase [J]. Carcinogenesis, 2005,26(1) : 229-238.
  • 2Zhang W,He XJ,Ma YY,et al.Inducible nitric oxide syn- thase expression correlates with angio-genesis,lymphan- giogenesis,and poor prognosis in gastric cancer patients [J]. Hum Pathol, 2011,42(9) : 1275-1282.
  • 3Shishodia S,Aggarwl BB.Cyclooxygenase(COX)-2 inhibitor celecoxib abrogates activation of cigarette smoke-induced nuclear factor(NF)-kappaB by suppressing activation of IkappaBalpha kinase in human non-small cell lung carci- noma: correlation with suppression of cyclin D1 ,COX-2, and matrix metalloproteinase-9 [J]. Cancer Res,2004, 64 (14) :5004-5012.
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  • 7Du Q,Zhang X, Cardinal J,el al. Wnt/beta-catenin signal- ing regulates cytokine-induced human inducible nitric ox- ide synthase expression by inhibiting nuclear factor-kap- paB activation in cancer cells[J]. Cancer Res,2009,69(9): 3764-3771.
  • 8陈祖尧,余玲,粱灼萍,刘文军,黎万荣,覃纲.环氧化酶-2和血管内皮生长因子在喉癌中的表达及临床意义[J].中国耳鼻咽喉头颈外科,2009,16(3):140-143. 被引量：5
  • 9杨径,王继华,王兰田,周伟雄.COX-2和iNOS在喉鳞癌中的表达及其与血管生成的相关研究[J].中国耳鼻咽喉颅底外科杂志,2009,15(2):97-102. 被引量：4
  • 10刘阳云,刘庚勋,李正贤,孙正良,周光华,江文.β-链接素、诱导型一氧化氮合酶与环氧合酶-2在鼻咽癌中的表达及临床意义[J].临床肿瘤学杂志,2010,15(4):310-314. 被引量：5

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中国耳鼻咽喉头颈外科
2008年 第7期

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