并发良性阵发性位置性眩晕的突发性聋患者预后相关性分析

Prognosis characteristics in idiopathic sudden sensorineural hearing loss patients with benign paroxysmal positional vertigo

目的探讨并发良性阵发性位置性眩晕(benign paroxysmal positional vertigo,BPPV)的突发性聋病例特征及BPPV与突发性聋预后相关性。方法对2007年3月~2013年3月,278例突发性聋病例进行回顾性分析。对治疗前及治疗后的纯音听阈结果进行分析,并对其预后进行多因素回归分析。结果 36例突发性聋病例并发BPPV(12.95%)。并发BPPV的突发性聋患者治疗前及治疗后听力损失重,并发BPPV的突发性聋者预后更差,多因素结果分析显示老龄(>60岁)、治疗前听力的损失程度、前庭功能异常与突发性聋预后密切相关。结论并发BPPV的突发性聋者,显示前庭功能受损更重,预后更差。

OBJECTIVE The purpose of this study is to investigate characteristics in patients with sudden sensorineural hearing loss(SSNHL),and to determine the role of benign paroxysmal positional vertigo(BPPV) as a prognostic factor in patients with SSNHL.METHODS We conducted a retrospective study of 278 patients with SSNHL.Hearing outcomes were evaluated by assessments of pre-treatment hearing and hearing gain.Comparative multivariate analyses between prognostic factors and hearing outcome were conducted.RESULTS Thirty-six(12.95%) SSNHL patients were found to have BPPV.BPPV showed significant negative prognostic factors in hearing outcome on multivariate analysis(odds ratio,0.15).In comparison to average pure tone audiometry(PTA),patients diagnosed with SSNHL with BPPV exhibited poorer hearing in pre- and post-treatment PTA compared to SSNHL without BPPV.Old age(>60years),pre-treatment hearing,and canal paresis were significant outcome predictors.CONCLUSION BPPV in SSNHL patients,representing definitive vestibular damage,was closely related to poor prognosis.