慢性鼻-鼻窦炎的细菌培养与药敏分析

Analysis of bacterial culture and antimicrobial susceptibility of chronic rhinosinusitis

目的分析慢性鼻-鼻窦炎的细菌学特点与药敏试验结果,为临床治疗提供依据。方法鼻内镜下采集中鼻道脓液进行细菌培养及药敏试验。结果 43例标本中,37例培养出细菌,细菌培养阳性率为86.04%;需氧菌株占91.90%,厌氧菌株占8.10%;共培养出20种细菌,主要为表皮葡萄球菌、铜绿假单胞菌、金黄色葡萄球菌。抗生素药敏试验显示抗菌活性较高的广谱抗生素为头孢哌酮舒巴坦钠、头孢呋辛钠。结论慢性鼻-鼻窦炎以需氧菌感染为主,应用抗生素宜先进行细菌培养和药敏试验,如情况不允许,可选择广谱的耐β-内酰胺酶类抗生素,如头孢哌酮舒巴坦钠、头孢呋辛钠等。

OBJECTIVE To analyze the bacteriological characters and drug sensitivity in patients with chronic rhinosinusitis and to provide basis for clinical treatment. METHODS The pur ulent discharges taken from middle meatus were cultured for bacteria and the drug sensitivity was determined. RESULTS In 43 specimens, the positive rate of bacter ia culture was 86.04%. Aerobic bacteria were present in 91.90%, anaerobic bacteria were present in 8.10%. A total of 20 bacteria were found in culture, mainly Epidermal Staphy, Pseudomonas aer uginosa, Staphylococcus aureus. The result of drug sensitivity demonstrated that Cefoperazone sulbactam, Cefuroxime sodium were good in vitro activity to aerobic bacteria. CONCLUSION The most common bacteria of chronic sinusitis are aerobic bacteria. Before treatment by antibiotics, the drug sensitivity should be performed. If the situation is not allowed, we should choose the broad-spectrum antibiotics that is resistance to β-lactam, such as Cefoperazone sulbactam, Cefuroxime sodium etc.