广州市变应性鼻炎患者舌下免疫治疗的依从性分析

Compliance to sublingual immunotherapy in patients with allergic rhinitis in Guangzhou city

目的探讨广州市变应性鼻炎(AR)患者进行舌下免疫治疗(sublingual immunotherapy,SLIT)的依从性。方法电话随访2014年1月~2014年5月接受尘螨滴剂SLIT的202例尘螨过敏AR患者,男100例,女102例,根据年龄分成A组(年龄<14岁)和B组(年龄≥14岁)。分析SLIT的依从性并调查影响依从性原因。结果 202例SLIT患者仅成功随访93例(46.04%),失访109例(53.96%)。成功随访93例中依从性好的比例为29.03%(27例),依从性差者70.97%(66例)。年龄及性别不影响SLIT依从性(P>0.05)。影响依从性的主要原因依次为疗效不佳(48.48%)、宣教知识不足(16.67%)、感觉用药麻烦(15.15%)、出现不良反应(10.61%)。结论广州市AR患者进行SLIT失访率很高;SLIT依从性很差,需要采取一些适当措施以提高SLIT依从性。

ABSTRACT]OBJECTIVETo study the compliance to sublingual immunotherapy(SLIT) in patients with allergic rhinitis(AR) in Guangzhou city.METHODSFrom January 2014 to May 2014, 202 patients with AR received SLIT were followed up by telephone. According to age, the patients were divided into group A(age<14 years) and group B(age≥14 years). The compliance to SLIT was analyzed and the reasons of poor compliance were investigated.RESULTSAmong 202 patients, only 93 cases(46.04%) were successfully followed up by telephone, 109 cases(53.96%) were lost to visit. Among the 93 cases of successful follow-up, the good compliance rate was 29.03%(n=27), the poor compliance rate was 70.97%(n=66). compliance to SLIT was not affected by age and gender(P>0.05). Main reasons for poor compliance included poor efficacy (48.48%), insufficient education about SLIT (16.67%), inconvenience (15.15%), and adverse reactions(10.61%).CONCLUSION In Guangzhou city, lost follow-up rate in AR patients receiving SLIT is high. Compliance to SLIT is relatively low and improvements shall be made.