咽喉反流性疾病患者精神心理状态分析

Analysis of mental state in patients with laryngopharyngeal reflux disease

目的通过对咽喉反流性疾病(laryngopharyngeal reflux disease,LPRD)患者的精神心理状态进行分析,明确LPRD患者是否存在焦虑、抑郁心理状态。方法就诊福州总院耳鼻咽喉头颈外科门诊的LPRD患者作为研究对象,同时选取相同例数到我院进行健康体检的健康志愿者作为对照组。对实验组及对照组进行焦虑自评量表(SAS)评分和抑郁自评量表(SDS)评分,研究LPRD患者的精神心理状态。结果 LPRD患者焦虑、抑郁评分均明显高于对照组(焦虑状态评分50.59±7.24 vs 38.76±7.70,抑郁状态评分52.90±7.14 vs 40.63±8.17)。LPRD患者焦虑、抑郁的发生率均明显高于对照组(焦虑发生率56.68%vs 9.80%,抑郁发生率50.98%vs 11.76%)。LPRD患者反流症状指数评分与焦虑、抑郁评分有明显相关性(r=0.786,r=0.736,P均<0.05),多因素分析证实LPRD与焦虑、抑郁评分之间存在显著的相关性。结论 LPRD患者较健康对照组更容易出现焦虑、抑郁的精神心理状态,且LPRD症状的严重程度与焦虑、抑郁的心理状态有明显相关性。这提示在常规抗酸治疗此类LPRD患者的同时,也应该重视对患者心理状态的干预。

OBJECTIVE To identify the mental state of laryngopharyngeal reflux disease(LPRD) patients by analyzing anxiety scale and depression scale. METHODS The LPRD patients who received treatment in Fuzhou General Hospital were studied. The healthy volunteers were recruited as control group. Self-rating Anxiety Scale(SAS)and Self-rating Depression Scale(SDS) were used to get the individual scores. Mental states of LPRD patients were finally studied through statistical analysis. RESULTS The scores of anxiety and depression in patients with LPRD were significantly higher than those in control group(anxiety score 50.59±7.24 vs 38.76±7.70, depression score52.90±7.14 vs 40.63±8.17). The incidence of anxiety and depression in patients with LPRD were significantly higher than that in control group(anxiety rate 56.68% vs 9.80%,depression rate 50.98% vs 11.76%). Significant association was detected between ref lux symptom index score and anxiety or depression score in patients with LPRD(r =0.786,r =0.736, P <0.05). Significant association between LPRD and anxiety and depression were concluded. CONCLUSION The results showed that the patients with LPRD are more prone to be anxiety and depression mental state than healthy control group, and the severity of LPRD symptoms is significantly correlated with the anxiety and depression.This suggests that the patient’s mental state should also be emphasized as well as antacids treatment.