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罂粟硷治疗阳萎的疗效指标及罂粟硷试验的剂量初探

Study of the Efficacous Objective Criterion of Intracavernous Papaverine Injection for Impotence and the Dosage of the papaverine test
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摘要 本文探讨了药物诱导阴茎勃起治疗阳萎时评价其疗效的几种临床客观指标,并对罂粟硷试验(PT)所用的药物剂量进行了比较。结果表明:罂粟硷局部注射治疗阳萎时,有效者的阴茎角度平均增加68^(68^±7.6).阴茎长度增加为5±0.6cm.阴茎中部直径增加1.1±0.02cm,阴茎中部直径增加率为45%±2.4%,阴茎长度增加率为74%±3%。与无效者比较有非常显著的差别(P<0.01)。以上五项指标均可作为评价疗效的简便而客观的指标。罂粟硷30mg 局注有效者仅24%。而60mg 局注有效者为59.3%(P<0.001).我们认为罂粟硷试验以60mg 较合理. The paper discussed some clinicalo bjective criterion which evaluated the efficacy of intracavernous pharmacotherapy for impotence,and the dosage of the papaverine test comparied in 78 patients with impotence.An erectil angle of the patients who provoked complete erection by intracavernous injection of 30 mg or 60 mg papaverine increased mean 68° (68°±7.6),the penile length 5 cm±0.16,the diameter of middle penis 1.1cm±0.02;the rate of the diameter 45%+2.4%,and the rate of penile length 74%±3%,respec- tively(P<0.01).The five indicaters may be take as objective and simple criterion to evaluate the clinical curative effect.In our series,24% of patients obtained fall erection after intracavernous injection of 30 mg papaverine,but 59.7% 60 mg papaverine(p<0.01).We consider that 60 mg papaverine test is more rational than 30 mg papaverine test.
出处 《医学科技》 1991年第24期21-23,共3页
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