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罂粟硷局部注射治疗阳萎所用剂量及其与并发症关系的探讨

The Dosage of Papaverine by Intracavernous Injection to Treat Impotence and Its Correlationship with Complications
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摘要 本文报告用婴粟硷或复方罂粟硷海绵体局注治疗97倒阳萎患者。对其药物的常用剂量与疗效和痛性勃起的关系作了比较。结果表明;单纯罂粟硷30mg 有效率为35%.60mg 为73%(P<0.001)。罂粟硷30mg 加酚妥拉明1mg 有效率为69%,罂粟硷60mg 加酚妥拉明1mg 有效率为76%(P>0.05).精神性阳萎总有效率为79%.器质性为45%.本组共发生痛性勃起13例(13.4%)15次(3.8次%).其中罂粟硷60mg 发生1次。复方罂粟硷发生12例14次(P<0.001).我们认为罂粟硷60mg 局注治疗阳萎为优。30mg 似不宜作治疗剂量,复方罂粟硷局注并不能提高疗效,且痛性勃起发生率明显增高.应慎用. We comparied the correlationship of the dosage of papaverine or papave- rine with phentolamine which treated 97 patients with impotence by intraca- vernous injection between the clinical efficacy and the complication of pri- apism.The results showed that 35% of the patients obtained full erection after in tracavernous injection of 30 mg papaverine,73% 60 mg papaverine(p< 0.001),69% 30 mg papaverine with 1 mg phentolamine,and 76% 60 mg papaverine with 1 mg phentolamine. On other hand,79% of patients with psychogenic impotence obtained full erection and 45% organic impotence (p<0.001)。In our series 13 patients (13.4%) had occured priapism after intracavernous injection and total 15 times,in whith One occured after intracavernous injection of 60mg papaverine, and others after papaverine with phentolamine. Authers consider that intracavernous injection of 60 mg papaverine trea- ting impotence is better than others.30 mg papaverine could not tahe as the dosage ef treatment for impotence,intracavernous injection of papaverine with phentolamine dose not increase curative effect,but the complication of priapism is increased obviously.
出处 《医学科技》 1991年第24期23-26,共4页
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