4-氨基-7-硝基苯并[1,2,5]噁二唑的合成

Synthesis of 4-Amino-7-nitrobenzo[1,2,5]oxadiazole

以 2 ,6-二氯苯胺为原料 ,通过氧化环化、硝化、叠氮化、氨化等 5步反应 ,得到 4-氨基 -7-硝基苯并 [1 ,2 ,5]二唑 ,并对反应条件、精制方法进行了改进。总收率 2 0 .1 %。

Amino 7 nitrobenzo[1,2,5]oxadiazole, an organic fluorescence reagents, was synthesized from 2,6 dichloroaniline by cyclization, nitration, azidation, and then amination with an overall yield of 20.1%.