术中应用地塞米松对儿童扁桃体切除术后疼痛的影响

Effects of Dexamethasone on Postoperative Pain after Tonsillectomy in Children

目的:探讨术中应用地塞米松对儿童扁桃体切除术后疼痛的影响。方法:选取我院2015年1月至2018年6月行双侧扁桃体切除术的50例患儿为研究对象,按入院先后顺序编号分为实验组和对照组各25例。两组患儿均采用相同麻醉方案,实验组术中应用地塞米松0. 5 mg/kg,最大剂量8. 0 mg,加入100 m L生理盐水中静脉滴注,分别记录患儿手术结束拔管后2 h、4 h及术后第1、2、3天每天8点患儿咽部疼痛程度并评分。结果:实验组术后4 h及术后第1、2天疼痛程度小于对照组(P<0. 05);术后2 h和术后第3天,两组患儿疼痛程度比较差异无统计学意义(P>0. 05)。结论:术中应用地塞米松能有效减轻儿童扁桃体切除术后疼痛。

Objective:To probe into the effects of intraoperative application of dexamethasone on postoperative pain after tonsillectomy in children.Methods:Totally 50 children undergoing bilateral tonsillectomy admitted into our hospital from Jan.2015 to Jun.2018 were extracted to be divided into the experimental group and the control group according to the admission sequence,with 25 cases in each group.Two groups were treated with the same anesthesia regimen.In the experimental group,dexamethasone 0.5 mg/kg was administered intraoperatively,and the maximum dose was 8.0 mg.And 100 m L of normal saline was added for intravenous infusion.The degree of pharyngeal pain was scored and recorded at 2 h,4 h after extubation,and 8:00 on the 1 st,2 nd,3 rdday after surgery.Results:The pain level of the experimental group was lower than that of the control group at 4 h after surgery and on the 1 stand 2 ndday after surgery(P<0.05).There was no statistically significant difference in pain degree between two groups at 2 h after surgery and on the 3 rdday after surgery(P>0.05).Conclusion:Intraoperative dexamethasone can effectively alleviate pain after tonsillectomy in children.