摘要
目的探讨脑梗死患者血清脂蛋白(a)水平及其与其他血脂的关系。方法:选择58例脑梗死患者及33例健康对照者测定其血清脂蛋白(a)、甘油三酯(TG)、总胆固醇(TC)、高密度脂蛋白胆固醇(HDL-C)、低密度脂蛋白胆固醇(IDL-C)、载脂蛋白Al(ApoAl)、载脂蛋白B(ApoB)水平。结果脑梗死组急性期Lp(a)水平27.8±25.8mg/dl,患者恢复期Lp(a)水平25.8±23.8mg/dl,二者之间没有显著差异;但二者与对照组比较有非常显著差异(Lp(a)水平为13.6±9.8mg/dl)(P<0.05)。Lp(a)水平除了与LDL-C呈正相关外,与其他血脂指标无明显的相关关系。结论 Lp(a)在脑梗死的致病因素上起重要作用。
Objective To study correlation between serum lipoprotein (a) levels and other blood lipids in patients with cerebral infarction. Methods Serum lipoprotein (a), triglyceride (TG), total cholesterol (TC), high density lipoprotein cholesterol (HDL- C), low density lipoprotein cholesterol (LDL- C), Apolipoproteins A- I and B were measured in 58 cases of cerebral infarction and 33 healthy control subjects. Results Lipoprotein (a) was 27.8 ± 25. 8mg/dl in acute attack period and it was 25.8 ± 23.8mg/dl in recovery period.There was no significant difference between them, but the levels of lipoprotein (a) were significantly higher than those in the control group (13.6± 9.8mg/dl) .There was a positive correlation btween lipoprotein (a) and LDL - C (r=0.35, P < 0.05) in patients with cerebral infarction. Conclusion Lipoprotein (a) Hays an important role in producing pathologic effect in cerebral infarction.
出处
《医学研究通讯》
2002年第9期13-14,共2页
Bulletin of Medical Research
