远志的化学成分研究(Ⅰ)(英文)

Studies on chemical constituents of root of Polygala tenuifolia (Yuanzhi) Ⅰ

目的 研究中药远志 Polygala tenuifolia根中的化学成分。方法 采用硅胶、Sephadex L H- 2 0及 ODS柱层析进行分离纯化 ,通过理化性质和光谱分析鉴定结构。结果 从中分离得到了 5个化合物 ,分别鉴定为 tenuifolisideB( ) ,3,4 ,5 -三甲氧基肉桂酸甲酯 ( ) ,polygalaxanthone ( ) ,7- O- methylmangiferin( )和 lancerin( )。结论 化合物 和 为首次从远志属植物中分离得到 ,化合物

Object To study the chemical constituents of the root of traditional Chinese medicine 'Yuanzhi' (Polygala tenuifolia Willd ) Methods Seperation and purification were performed on silica gel, Sephadex LH 20 and ODS CC Their structures were established on the basis of physicochemical and spectral analysis Results Five compounds were isolated and identified as tenuifoliside B (Ⅰ), methyl 3, 4, 5 trimethoxycinnamate (Ⅱ), polygalaxanthone Ⅲ (Ⅲ), 7 O methylmangiferin (Ⅳ) and lancerin (Ⅴ), respectively Conclusion Compounds Ⅱ and Ⅳ were isolated from the plant of Polygala L for the first time and compound V was isolated from P tenuifolia for the first time