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轴突转运和糖尿病神经病变 被引量：2

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摘要 本文复习了近二十年来有关轴突转运与糖尿病神经病变的研究,重点介绍了糖尿病神经病变时轴突慢转运和快转运损伤的表现以及药物对轴突转运的干预作用。
作者 张云云 蒋雨平 等
机构地区 复旦大学附属华山医院神经内科
出处 《国外医学（神经病学．神经外科学分册）》 2002年第5期448-451,共4页 Foreign Medical Sciences（Section On Neurology & Neurosurgery）
关键词 轴突转运 糖尿病神经病变 DN 快转运损伤 药物干预
分类号 R587.2 [医药卫生—内分泌]
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参考文献11

  • 1Yamamoto Y, Yasuda Y, Komiya Y. Cilostazol prevents impairment of slow sxonal transport in streptozotocin- diabetic rats. Eur J Pharmacol, 2000, 409(1): 1-7.
  • 2Abbate SL, Atkinson MB, Breuer AC. Amount and speed of fast axonal transport in diabetes. Diabdtes, 1991, 40(1): 111-117.
  • 3Zhang L, Ino- ue M, Dong K, et al. Retrograde axonal transport impairment of large- and medium- sized retinal ganglion cells in diabetic rat. Curr Eye Res, 2000, 20(2): 131-136.
  • 4Lee PG, Cai, Helke CJ. Streptozotocin-induced diabetes reduces retrograde axonal transport in the afferent and efferent vagus nerve. Brain Res, 2002, 941(1-2): 127-136.
  • 5Hellweg R, Baivich G, Hartung HD, et al. Axonal transport of endogenous nerve growth factor (NGF) and NGF receptor in experimental diabetic neuropatthy. Exp Neurol, 1994, 130(1): 24-30.
  • 6Delcroix JD, Tomlinson DR, Femyhough P. Diabetes and axotomy- induced deficits in retrograde axonal transport of nerve growth factor correlate with decreased levels of p75LNTR protein in lumbar dorsal root ganglia. Brain Bes Mol Brain Bes, 1997, 51(1-2): 82-90.
  • 7Fernyhough P, Diemel LT, Tomlinson DR, et al. Target tissue preduction and axonal transport of neurotrophin - 3 are reduced in streptozotocin - diabetic rats. Diabetologia, 1998, 41(3): 300-306.
  • 8Lee PG, Hohman TC, Cai F, et al. Streptozotocin- induced diabetes causes metabolic changes and alterations in neurotrophin content and retrograde transport in the cervical vagus nerve. Exp Neurol, 2001, 170(1): 149-161.
  • 9Mizisin AP, DiStefano PS, Liu X, et al. Decreased accumulation of endogenous brain - derived neuotrophic factor against constricting sciatic nerve ligatures in streptozotocin - diabetic and galactose - fed rats. Neurosci Lett, 1999, 263(2-3): 149-152.
  • 10Ino-Ue M, Zhang L, Naka H, et al. Polyol metabolism of retograde axonal transport in diabetic rat large optic nerve fiber. Invest Ophthalmol Vis Sci, 2000, 41(13): 4055-4058.

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国外医学（神经病学．神经外科学分册）
2002年 第5期

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