白细胞介素-6与缺血性脑血管病
摘要
淋巴细胞与多种非淋巴细胞都能自发或在其他因素的刺激下产生白细胞介素-6(IL-6),IL—6生物学活性是由其受体(IL—6R)介导,主要通过Jak/STAT信号传导途径等引起DNA转录表达。缺血性脑损伤时IL—6在脑脊液、血清、脑组织中的表达水平增高,炎症反应明显;抗IL—6抗体能明显减小脑梗死体积,减轻脑水肿。
出处
《神经疾病与精神卫生》
2002年第5期313-315,共3页
Journal of Neuroscience and Mental Health
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