幽门螺杆菌与小儿反复性腹痛关系的研究

A Clinical Study on Association of Helicobacter pylori with Recurrent Abdominal Pain in Children

目的 :探讨幽门螺杆菌 (HP)与小儿反复性腹痛的关系 ,为小儿反复性腹痛的诊断、治疗提供依据。方法 :采用福建兰波生物制剂厂生产的HP抗体药盒 ,用金标法测定 2 31例反复性腹痛患儿HP IgM ,HP IgG ,80例健康儿童作对照。结果 :反复性腹痛患儿HP IgM阳性率 6 6 .2 3% ,HP IgG阳性率为 6 1.0 4 % ;对照组HP IgM阳性率为 4 2 .5 % ,HP IgG阳性率为 38.92 % ,两组比较有显著性差异 (P <0 .0 0 5 )。 结论

Objective:To determine the relationship between helicobacter pylori (HP)and recurrent abdominal pain(RAP) in children so as to help to improve the diagnosis and treatment of RAP Methods: Serum and HP IgM ,IgG antibodies of 231 RAP children and 80 healthy children were measured by Golden level method with HP antibody kit made by Nan Bo Factory in FuJan. Results: The positive rates of HP IgM,IgM and IgG of 231 RAP children were 66 23%,42 5%,and 38 92% respectively The difference was statistically significant between these two groups(P<0.005) Conclusion:RAP is closely related to HP infection in children.