雷公藤碱丁和碱辛的结构

Structures of Wilfortrine and Neowilforine from Tripterygium wilfordii Hook. f.

前已报道雷公藤(Tripterygium wilfordii Hook.f.)中雷公藤碱(wilfordine,1)、次碱(wilforine,2)、碱乙(wilforgine,3)、碱戊、碱己和碱庚的分离和结构。本文报道雷公藤碱丁(wilfortrine,4)和碱辛(neowilforine,5)的结构测定。5是一新生物碱。 4和5的红外光谱均显示1745和1240cm^(-1)内酯吸收。4的质谱与1类同。

Two alkaloids, wilfortrine (4) and neowilforine (5)were isolated from Tripterygium wilfordii Hook. f., Their structures were elucidated by chemical methods and spectroscopic analyses. 5 is a new alkaloid.