Lactate Dehydrogenase Isoenzyme of Lens in Fetus

Purpose: The LDH isoenzyme patterns were evaluated in lens of fetus to study the metabolism in human lenses.Methods: LDH isoenzyme electrophoresis was performed in 15 lenses of human fetus aged from 4～6 months.Results: There are 5 bands of LDH in fetus lens. LDH4 lever is the highest, and LDH1 is the lowest, especially in the cortex of lens. LDH1 is higher in lens of 4 months of age than in that of 5 and 6 months of age.Conclusions: LDH isoenzyme in lens of fetus shows mainly anaerobic metabolism in development, but there is also aerobic metabolism, especially in younger fetus.

Purpose: The LDH isoenzyme patterns were evaluated in lens of fetus to study the metabolism in human lenses. Methods: LDH isoenzyme electrophoresis was performed in 15 lenses of human fetus aged from 4-6 months. Results: There are 5 bands of LDH in fetus lens. LDH4 lever is the highest, and LDHr is the lowest, especially in the cortex of lens. LDHi is higher in lens of 4 months of age than in that of 5 and 6 months of age. Conclusions: LDH isoenzyme in lens of fetus shows mainly anaerobic metabolism in development, but there is also aerobic metabolism, especially in younger fetus. Eye Science 2002; 18: 194 - 196.