食盐加碘10年对地方性甲状腺肿和甲状腺功能亢进症患病率的影响

The effect of salt iodization for 10 years on the prevalences of endemic goiter and hyperthyroidism

目的 观察食盐加碘对地方性甲状腺肿 (地甲病 )和甲状腺功能亢进症 (甲亢 )患病率的影响。方法 1989年调查了福州市 (10 4 5 4人 )和武夷山市 (10 32人 )两地共 114 86人的甲状腺肿和甲状腺功能亢进症的患病率 ,经过普遍食盐加碘 10年后 ,又以同样方法对两地进行调查 (福州3473人 ,武夷山 2 394人 ,两地共 5 86 7)。结果 普遍食盐加碘 10年后 ,福州市的甲亢患病率从 0 .5 7%增至 1.0 9% (P <0 .0 1) ,武夷山市地甲病患病率由 2 4 .5 1%减至 11.5 8% (P <0 .0 1)。结论普遍食盐加碘使地甲病患病率明显降低 ,但甲亢的患病率增加 ,这可能部分与碘摄入增多有关。

Objective To observe the effects of salt iodization on the prevalence of endemic goiter and hyperthyroidism. Methods The prevalences of endemic goiter and hyperthyroidism were investigated in 10454 subjects in Fuzhou and 1032 subjects in Wuyishan in 1989. After 10 years of universal salt iodization (USI), the survey was done again in these two regions covering 3473 subjects in Fuzhou and 2394 subjects in Wuyishan with the same methods. Results After 10 years of USI, the prevalence of hyperthyroidism was increased from 0.57% to 1.09% in Fuzhou (P<0.01),andthatofendemicgoiter was decreased from 24.51% to 11.58% in Wuyishan (P<0.01). Conclusion After 10 years of USI the prevalence of endemic goiter decreases significantly, but the prevalence of hyperthyroidism increases, which may be partly related to increased iodine intake.