摘要
乳腺癌是多步骤发生的疾病,存在多个生物学因子的异常。研究生物学预后因子不仅能发现临床病理学指标不能发现的部分易复发患者,而且有助于实施乳腺癌的个体化治疗。本文综述乳腺癌生物学预后因子,如Her-2/neu、P53、BRCA1、血管生成因子(angiogenesis)杂合性丢失(LOH)等的最新进展。
Breast cancer is a multistep process with abnormalities of some biomarkers.Knowledge of biomarkers can provide prognostic information in addition to the clinicopathologic factors,and is useful to carry out the indiviual treat- ment.In this review,we summarized the most recent work in the field of biological markers used for the prognosis,such as Her-2/neu,P53,BRCA1,Angiogenesis,LOH,et al
出处
《中国癌症杂志》
CAS
CSCD
2002年第5期465-469,共5页
China Oncology