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乳腺癌生物学预后因子的研究进展

Advances of the biological prognostic factors in breast cancer
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摘要 乳腺癌是多步骤发生的疾病,存在多个生物学因子的异常。研究生物学预后因子不仅能发现临床病理学指标不能发现的部分易复发患者,而且有助于实施乳腺癌的个体化治疗。本文综述乳腺癌生物学预后因子,如Her-2/neu、P53、BRCA1、血管生成因子(angiogenesis)杂合性丢失(LOH)等的最新进展。 Breast cancer is a multistep process with abnormalities of some biomarkers.Knowledge of biomarkers can provide prognostic information in addition to the clinicopathologic factors,and is useful to carry out the indiviual treat- ment.In this review,we summarized the most recent work in the field of biological markers used for the prognosis,such as Her-2/neu,P53,BRCA1,Angiogenesis,LOH,et al
作者 张杰 邵志敏 沈镇宙
机构地区 复旦大学附属肿瘤医院乳腺外科
出处 《中国癌症杂志》 CAS CSCD 2002年第5期465-469,共5页 China Oncology
关键词 乳腺癌 生物学因子 预后因子 癌基因 抑癌基因 breast cancer biomarker prognostic factor
分类号 R737.9 [医药卫生—肿瘤]
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中国癌症杂志
2002年 第5期

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