糖尿病人群伴发抑郁症的临床研究

A study on depression among diabetic population

目的 了解我国糖尿病人群抑郁症的患病率 ,探讨糖尿病与抑郁症之间的相互关系。 方法 应用汉密尔顿抑郁量表对 6 11例糖尿病患者和 4 2 9例其他躯体疾病患者进行调查评定 ,并对其相关因素进行分析。 结果 (1)糖尿病和其他各躯体疾病者抑郁症的患病率 :糖尿病组 2 8.6 % ,高血压病组 9.8% ,甲状腺功能亢进组 9.4 % ,慢性阻塞性肺病组 7.8% ,缺铁性贫血组 11.5 %。糖尿病组抑郁症的患病率高于其他躯体疾病组 ,差异有非常显著性意义 (P<0 .0 1)。 (2 )在糖尿病人群中 ,抑郁症的发生与女性、文化程度、体重指数 >2 5 kg/ m2 、糖化血红蛋白 >8%、慢性并发症增加密切相关。 结论 抑郁症在糖尿病人群中有较高的患病率 。

Objective To investigate the prevalence rate of depression in Chinese diabetic population and the relationship between diabetes mellitus (DM) and depression. Methods 611 cases with diabetes mellitus and 429 cases with different somatic diseases were interviewed and analyzed by Hamilton Depression Scale (HAMD). Results (1)The prevalence rates of depression in diabetes mellitus and different somatic diseases were 28.6% in DM, 9.8% in EHT (E), 9.4% in hyperthyroidism (T), 7.8% in COPD (C), and 11.5% in iron deficiency anemia. (2) Among all the subjects, the prevalence rate of depression in diabetic subjects was higher than other somatic diseases ( P <0.01). (3) Depression was found to be correlated with five factors in diabetic patients, which were woman, BMI>25, higher education level, HbA1c>8%, diabetic complications. Conclusion The prevalence rate of depression in diabetic patients is higher than other somatic diseases; depression plays an important role in the development and prognosis of DM.