摘要
本室曾在光镜水平上显示,犬腺垂体远侧部P物质样免疫反应多膨体神经纤维与腺细胞关系极为密切。本实验应用包埋前免疫组织化学电镜法,进一步研究了这种神经纤维的超微结构,及其与腺细胞的关系。本文发现P物质样免疫反应多膨体神经纤维与各种腺细胞以及滤泡星形细胞发生直接接触,与促生长激素细胞和促肾上腺皮质激素细胞有典型的突触结构,其中与后者构成的突触较多。大多数突触为不对称型,含有圆形或椭圆形清亮小泡和大致密芯泡。本实验结果表明,犬腺垂体远侧部P物质样免疫反应神经纤维对腺细胞活动有直接调节作用。
In our previous studies, substance P-like immunoreactive varicose nerve fibers have been demonstrated in the pars distalis of the adenohypophysis of the dog. They were found, at light microscopical level, to be closely related to gland cells. In the present study, the ultrastructure of substance P-like immunoreactive nerve fibers and their relationship with the gland cells of the pars distalis in the dog were investigated by use of pre-embedding immuno-electron microscopy. Direct contacts could be ascertained on every cell type of the gland, including folliculo-stellate cells. Typical synapses were identified on somatotropes and corticotropes, more on the latter. Most of them were of asymmetrical type with round to oval small clear vesicles and scattered large dense cored vesicles. It is considered morphologically proved that the substance P-like immunoreactive nerve fibers have effector role in the pars distalis of the dog.
出处
《解剖学报》
CAS
CSCD
北大核心
1991年第2期161-165,I005,6,共7页
Acta Anatomica Sinica
基金
国家自然科学基金
关键词
腺垂体远侧部
神经支配
P物质
犬
Pars distalis of adenohypophysis
Innervation
Substance P
Immunoelectron microscopy
Dog