儿童癫痫脑电图改变及治疗效果相关性研究

目的分析儿童癫痫脑电图(electroencephalo graphy,EEG)改变与治疗效果的相关性。方法选取癫痫患儿40例,均给予抗癫痫药物(Anti epileptic drugs,AEDs)治疗。分别于治疗前后对所有患儿进行EEG检查,分析EEG与治疗效果的相关性。结果 (1)根据治疗前EEG检查结果分为EEG正常组(5例)和EEG异常组(35例),2组治疗总有效率差异无统计学意义(100.00%vs 71.43%);(2)根据治疗后EEG改变情况分为EEG恢复正常组(17例)和EEG持续异常组(23例),2组治疗总有效率差异有统计学意义(94.12%vs 60.87%,P<0.05)。结论 EEG异常是影响儿童癫痫治疗效果的重要因素,尤其是EEG持续异常,危害更大。

Objective To analyze the correlation between EEG changes and therapeutic effect in children epilepsy. Methods 40 children with epilepsy. All patients were treated with AEDs. Before and after treatment, all the patients were examined by EEG, and the correlation between the EEG and the treatment effect was analyzed. Results (1)All patients divided into normal EEG group (5 cases) and abnormal EEG group (35 cases) according to the results of EEG examination before treatment, the total effective rate in the two groups had no significant difference (100.00% vs.71.43%). (2)All patients were divided into EEG normal group (17 cases) and EEG continuous abnormal group (23 cases) according to the change of EEG after treatment. The total effective rate was significantly different between the two groups (94.12% vs. 60.87%, P<0.05). Conclusion EEG abnormality is an important factor that affects the treatment effect of children with epilepsy, especially the EEG continues to be abnormal, and the harm is even greater.