红细胞分布宽度和左心房容积指数与非瓣膜性心房颤动的关系

Relationship between RDW, LAVI and Non-valvular Atrial Fibrillation

目的:探讨红细胞分布宽度(RDW)和左心房容积(LAV)指数(LAVI)与心房颤动(AF)间的关系,筛选早期预测AF的指标。方法:108例非瓣膜性阵发性AF的患者为AF组和84例无AF患者为对照组,两组均进行体格检查和超声心动图影像学检查,全血细胞计数分析了RBC、RDW、中性粒细胞、中性粒细胞/淋巴细胞比值(NLR)及平均红细胞体积。比较两组人口学资料和超声心动图的资料。结果:AF组LAV、LAVI、RDW和hs-CRP均显著高于对照组(P<0.05)。两组NLR比较无明显差异(P>0.05)。多元Logistic回归分析显示:升高的LAVI、RDW和hs-CRP是非瓣膜性AF发生的独立预测因子。结论:升高的RDW水平和升高的LAVI可能是独立的非瓣膜性AF发生的预测危险因素。

Objective: To investigate the relationship between red cell distribution width(RDW), left atrial volume(LAV) index(LAVI)and non-valvular atrial fibrillation(AF) and screen the early predictor of AF.Methods:108 cases of patients with non-valvular paroxysmalAF(AF group) and 84 cases without AF patients as control group, two groups were performed physical examination and echocardiograhy,blood cell count analysis the RBC, RDW, neutrophils, neutrophil/lymphocyte ratio (NLR) and mean red cell volume.Comparison ofdemographic data and echocardiography in two groups.Results:LAV LAVI, RDW and hs-CRP in group AF were significantly higher thanthose in control group (P<0.05).There was no significant difference in NLR between the two groups (P>0.05).Multivariate Logisticregression analysis showed that elevated LAVI, RDW and hs-CRP were independent predictors of the occurrence of non-valvularAF.Conclusion:Increased RDW levels and elevated LAVI may be the independent risk factors for non-valvular AF.