化瘀调冲任汤治疗肝郁血瘀型痛经的临床研究

Clinical Study on Huayutiaochongren Decoction in the Treatment of Liver Depression and Blood Stasis Dysmenorrhea Regulating Stasis

目的:探讨陈定潜老师自拟方化瘀调冲任汤治疗肝郁血瘀型痛经的临床疗效。方法:89例肝郁血瘀型原发性痛经患者,随机分为西药对照组(A组)和中药治疗组(B组),B组以化瘀调冲任汤治疗,A组予以布洛芬缓释胶囊口服,疗程均为3个月经周期,随月经周期间断服药。运用组间和治疗前后自身疼痛VAS评分量表、COX痛经症状量表、中医证候疗效评分变化对照来评定疗效,停药后随访3个月经周期。结果:B组运用化瘀调冲汤治疗后腹部疼痛程度和其他伴随症状服药前相比明显改善,效果优于A组,服药时间越长越明显,停药后3个月效果稳定。两组的组间对比均具有统计学差异,B组服药12周总有效率达91.11%,痊愈率53.33%,未见不良反应。结论:化瘀调冲任汤可起到良好的疏通肝络、理气活血、调理冲任之功效,完全或部分减缓解经腹痛的症状,除行经腹痛的减轻,其他伴随症状也得到不同程度的缓解,是中医药干预治疗肝郁血瘀型痛经安全有效的治疗方案。

Objective: To investigate the clinical effect of self-made Huayutiaochongren Decoction of Chen Ding-qian teacher inthe treatment of liver depression and blood stasis dysmenorrhea. Methods: 89 cases of liver depression and blood stasis type primarydysmenorrhea patients, randomly divided into western medicine control group (group A) and traditional TCM group (group B), group Bto Huayutiaochongren Decoction in the treatment of, group A was treated with oral administration of ibuprofen sustained release capsules,were treated for three menstrual cycles, with the month the week off medication. The therapeutic effect was evaluated by the group andthe self pain VAS score scale, COX symptom scale, TCM syndrome curative effect score, and 3 menstrual cycles were followed up afterwithdrawal. Results: The group B used to remove blood stasis in the treatment of abdominal pain and other symptoms compared with othersymptoms significantly improved, the effect is better than the A group, the longer the time, the more obvious, 3 months after withdrawaleffect. In the two groups, there were statistically significant differences between the groups, the total effective rate of B group was 12,the cure rate was 53.33%, and no adverse reaction was found. Conclusions:Removing blood stasis and regulating Chong soup Keqi togood dredging liver meridian, Qi and activating blood, regulating effect of Chong and Ren, completely or partially slow solution by thesymptoms of abdominal pain, in addition to the line of the abdominal pain relief, other accompanied symptoms were different degrees ofease, the intervention of traditional TCM of liver depression and blood stasis type dysmenorrhea is a safe and effective treatment.