血清肌酸激酶、C-反应蛋白和D-二聚体水平的测定在绞窄性肠梗阻早期诊断中的应用价值

Application value of level determination of serum creatine kinase, C-reactive protein and D-dimer in the early diagnosis of strangulated intestinal obstruction

目的:分析血清肌酸激酶、C-反应蛋白和D-二聚体水平的测定在绞窄性肠梗阻早期诊断中的应用价值。方法:选择我院2013年4月—2015年4月收治的35例绞窄性肠梗阻患者作为观察组研究对象,和同期收治的35例单纯性肠梗阻患者作为实验组研究对象,同时,收集我院行血清肌酸激酶、C-反应蛋白和D-二聚体水平检查的健康志愿者30例进行对照组。所有患者均接受血清肌酸激酶、C-反应蛋白和D-二聚体水平测测定,比较其检查结果,并分析三指标之间的相关性。结果:实验组与对照组相比,两组患者血清肌酸激酶、C-反应蛋白和D-二聚体水平无明显差异(P>0.05),而观察组患者血清肌酸激酶、C-反应蛋白和D-二聚体水平水平均显著高于实验组和对照组,差异有统计学意义(P<0.05)。观察组患者血清肌酸激酶、C-反应蛋白和D-二聚体水平三指标间成正相关。结论:通过检测患者血清肌酸激酶、C-反应蛋白和D-二聚体水平等水平能够有效确定绞窄性肠梗阻,并能准确判断患者损伤程度,为患者后期治疗提供有效信息,值得临床推广。

Objective: To analyze the value of level determination of serum creatine kinase, C-reactive protein and D-dimer in theearly diagnosis of strangulated intestinal obstruction. Methods: 35 cases of strangulating intestinal obstruction patients admitted in ourhospital from April 2013 to 2015 April were treated as observation group, and 35 patients admitted during the same period with simpleobstruction were taken as the experimental group. Serum creatine kinase, C- reactive protein and D- dimer levels of 30 cases of healthyvolunteers were examined as a control group. All patients received serum creatine kinase, C- reactive protein and D- dimer levels measuredto compare their test results and analyze the correlation between the three indicators. Results: Compared with the control group, the levelsof serum creatine kinase, C- reactive protein and D- dimer were not significantly different (P>0.05), while the serum creatine kinase, Creactiveprotein and D- dimer levels of the observation group were significantly higher than those in the experimental group and the controlgroup, the difference was statistically significant (P<0.05). The serum creatine kinase, C-reactive protein and D-dimer levels of theobservation group among the three indexes were positively correlated. Conclusion: The detection of serum creatine kinase, C- reactiveprotein and D- dimer levels can effectively determine the level of strangulating intestinal obstruction, accurately determine the degree ofinjury patients and provide useful information for the treatment of late stage patients which is worthy of promotion.