妇科围手术期DVT高危因素分析及速碧林临床应用预防价值评价

DVT high risk factors analysis in gynecological perioperative period and evaluation of the prevention value of the clinical application of nodroparin

目的:探讨妇科围手术期深静脉血栓形成(Deep Venous Thrombosis,DVT)高危因素分析及速碧林临床应用预防价值。方法:回顾性分析2012年9月—2015年10月于我院妇产科治疗的40例高危患者为研究对象,对全部患者使用速碧林预防治疗。结果:深静脉血栓是妇科围手术期高危因素,经单因素分析,深静脉血栓的发生与恶性肿瘤、预防措施、制动时间长、手术时间过长、术中出血量多、围术期输血量大等因素有关,以上单因素分析差异有统计学意义(P<0.05)。将研究患者分为4个等级,低危、中危、高危与极高危,按患者等级进行速碧林注射治疗,治疗后患者发生率、并发症,差异无统计学意义(P>0.05)。结论:深静脉血栓是妇科围手术期DVT高危因素,速碧林能有效预防深静脉血栓,安全性高、状况明显改善,值得临床推广应用。

Objective: To investigate the high risk factors of deep venous thrombosis (DVT) in gynecological perioperative periodand to evaluate the prevention value of the clinical application of nodroparin. Methods: 40 patients with DVT, treated in our hospital fromDecember 2012 to October 2015, were selected as the research objects and retrospectively analyzed; all patients received nodroparin aspreventive treatment. Results: DVT was high risk factor in gynecological perioperative period, single factor analysis indicated that theincidence of DVT was related to factors such as malignant tumor, preventive measures, long braking time, long operation time, bleedingvolume during operation, perioperative blood transfusion, the above single factor analysis was of statistical difference (P<0.05). Patientswere divided into 4 grades, low risk, medium risk, high risk and very high risk, all patients received nodroparin treatment according to therisk grades, the difference in the incidence rate and complication of patients after treatment was of no statistical difference (P>0.05).Conclusion: DVT was high risk factor in gynecological perioperative period, nodroparin could prevent DVT effectively, it was of highsecurity and could relieve the patient's symptoms significantly, therefore, it was worthy of clinical promotion and application.