小剂量阿司匹林联合用药治疗与预防脑梗死的临床效果分析

Clinical effect analysis of small-dose aspirin combination therapy in the treatment and prevention of cerebral infarction

目的:探讨小剂量阿司匹林联合用药治疗与预防脑梗死的临床效果分析。方法:2013年1月-2014年1月收治脑梗死患者128例,随机分为观察组与对照组,每组64例。对照组给予常规剂量阿司匹林,观察组采用小剂量阿司匹林联合低分子肝素治疗,比较两组患者脑梗死治疗、不良反应及脑梗死复发的预防效果。结果:观察组神经功能缺损评分明显优于对照组,且治疗总有效率高于对照组,差异具有统计学意义(P<0.05)。观察组脑梗死复发率及不良反应发生率明显低于对照组,差异具有统计学意义(P<0.05)。结论:采用小剂量阿司匹林联合用药治疗脑梗死具有较好的临床效果,较安全,不良反应发生率及复发率较低,具有临床应用及推广价值。

Objective:To explore clinical effect of low-dose aspirin combination therapy in the treatment and prevention of cerebral infarction.Methods:128 cases of patients with cerebral infarction from January 2013 to January 2014 were randomly divided into the observation group and the control group,with 64 cases in each group.The control group were given routine dose of aspirin,and the observation group were given low-dose aspirin with low molecular heparin therapy.The treatment,adverse reaction and prevention effect of cerebral infarction recurrent in the two groups were compared.Results:The neural function defect scale of the observation group was obviously superior to that of the control group,the total effective rate was higher than that of the control group,there were statistically significant differences(P<0.05).The recurrence incidence of cerebral infarction rate and adverse reaction of the observation group were obviously lower than that of the control group,and the differences were statistical significant(P<0.05).Conclusion:Low-dose aspirin combination therapy in the treatment of cerebral infarction had good clinical effect and was safer,and the incidence of adverse reactions and the recurrence rate were lower,which had clinical application and popularization value.