角膜缘干细胞移行遮盖法联合丝裂霉素C治疗翼状胬肉的观察

Observation of limbal stem cell migration shaded combined with mitomycin C in the treatment of pterygium

目的:比较角膜缘干细胞移行遮盖法联合丝裂霉素C和翼状胬肉切除术联合丝裂霉素C对初发性翼状胬肉的疗效。方法:收治初发性翼状胬肉患者122例,随机分两组,各61例,对照组给予翼状胬肉切除术联合丝裂霉素C,观察组则给予角膜缘干细胞移行遮盖法联合丝裂霉素C,术后随访12个月,对比治疗效果、复发率、角膜创面恢复时间。结果:观察组治疗总有效率高于对照组,无复发情况发生,角膜创面恢复时间短于较对照组(P<0.05)。结论:角膜缘干细胞移行遮盖法联合丝裂霉素C在翼状胬肉治疗中的效果显著。

Objective:To compare the effect of limbal stem cell migration shaded combined with mitomycin C with pterygiumexcision with mitomycin C in the treatment of pterygium.Methods:122 patients with primary pterygium were selected,they wererandomly divided into two groups,each of 61 cases,the control group received pterygium excision with mitomycin C,theobservation group were treated with limbal stem cell migration shaded with mitomycin C,postoperative follow up 12 months,comparing to treatment effect,the recurrence rate,corneal wound recovery time.Results:The total effective rate in observation groupwas higher than that in control group,no recurrence occurred,and the recovery time of corneal wound was shorter than that incontrol group(P<0.05).Conclusion:The effect of limbal stem cell migration shaded combined with mitomycin C in the treatment ofpterygium is outstanding.