长托宁与阿托品治疗有机磷中毒的临床疗效对比

Comparison of the clinical curative effect of penehyclidine hydrochloride and atropine in the treatment of organophosphorus poisoning

目的:探讨长托宁与阿托品治疗有机磷中毒的效果。方法:收治有机磷中毒患者34例,随机分成两组,各17例,对照组给予阿托品治疗,观察组给予长托宁治疗,观察两组治疗效果及不良反应。结果:观察组的治愈率明显高于对照组,且观察组的住院天数、用药次数、病死率和不良反应情况均明显优于对照组(P<0.05)。结论:有机磷中毒患者采取长托宁治疗效果明显,安全、有效。

Objective:To explore the effect of penehyclidine hydrochloride and atropine in the treatment of organophosphorus poisoning.Methods:34 patients with organophosphorus poisoning were selected.They were randomly divided into two groups with 17 cases in each.The control group was given atropine treatment.The observation group was given penehyclidine hydrochloride treatment.The curative effects and adverse reactions of the two groups were observed.Results:The cure rate of the observation group was significantly higher than that of the control group,and the hospitalization day,medication time,mortality and adverse reaction of the observation group were significantly less than those of the control group(P<0.05).Conclusion:Using penehyclidine hydrochloride in patients with organophosphorus poisoning has a obvious curative effect.It is safe and effective.