冠心泰对不稳定性心绞痛患者颈动脉内膜中层厚度及正五聚蛋白-3的影响

Impact of Guanxintai on carotid artery intima media thickness and pentraxin-3 in patients with unstable angina pectoris

目的:探讨冠心泰对不稳定性心绞痛患者颈动脉内膜中层厚度及正五聚蛋白-3的影响。方法:收治不稳定性心绞痛患者120例,随机均分为对照组和治疗组各60例。对照组给予常规西药治疗,治疗组给予常规西药组加用冠心泰丸。结果:治疗后对照组和治疗组的IMT厚度及PTX-3低于治疗前水平(P<0.05),且治疗组的IMT厚度及PTX-3水平低于对照组(P<0.05)。结论:冠心泰治疗不稳定性心绞痛的疗效显著,可降低患者的颈动脉内膜中层厚度及正五聚蛋白-3水平。

Objective:To investigate the effect of Guanxintai on carotid artery intima media thickness and pentraxin-3 in patients with unstable angina pectoris.Methods:120 patients with unstable angina were selected.They were randomly divided into the control group and the treatment group with 60 cases in each.Patients in the control group were given conventional western medicine treatment,while in the treatment group were treated with conventional western medicine added Guanxintai pill.Results:After the treatment,the thickness of IMT and PTX-3 in the control group and the treatment group were significantly lower than before the treatment(P<0.05),and the thickness of IMT and PTX-3 in the treatment group were lower than in the control group(P<0.05).Conclusion:Guanxintai has significantly curative effect on unstable angina pectoris,and it can reduce the carotid artery intima media thickness and the level of pentraxin-3.