小儿高热惊厥应用双氯芬酸钠栓剂的近期疗效与安全性观察

Short term curative effect and safety observation of application of diclofenac sodium suppository in infantile febrile convulsion

目的:研究小儿高热惊厥应用双氯芬酸钠栓剂的近期疗效与安全性。方法:收治高热惊厥患儿106例,随机分为对照组与研究组各53例,对照组给予25%安乃近滴鼻治疗,研究组给予双氯芬酸钠栓剂塞肛治疗,对比两组疗效。结果:两组的临床总好转率差异无统计学意义(P>0.05);研究组的呕吐、多汗发生率明显低于对照组(P<0.05)。结论:小儿高热惊厥应用双氯芬酸钠栓剂治疗有助于减少惊厥发作,降低体温,且安全性较高。

Objective:To study the short term curative effect and safety of application of diclofenac sodium suppository in infantilefebrile convulsion.Methods:106 children patients with febrile convulsion were selected.They were randomly divided into thecontrol group and the study group with 53 cases in each.The control group was given 25% analgin nasal drop treatment.The studygroup was given diclofenac sodium suppository plug anal treatment.The curative effects were compared between groups.Results:The total improvement rates of two groups showed no significant difference(P>0.05).The occurrence rates of vomiting, sweating inthe study group were significantly lower than those of the control group(P<0.05).Conclusion:The application of diclofenac sodiumsuppository in the treatment of infantile febrile convulsion can help to reduce the seizures,reduce the hypothermia,and its safety ishigh.