医院不合理用药多因素分析及防范措施

Multiple-factors analysis and preventive measures of hospital irrational drug use

目的:分析医院不合理用药情况,采取干预措施,提高合理用药水平。方法:随机抽查4 586张处方,筛选出用药不合理的处方,分析其用药不合理原因,探讨防范措施,制定合理用药方案。结果:用药不合理处方268张,不合格率5.84%。存在的不合理现象有给药时间间隔不当、滥用抗生素、药物剂量不当、药物选用不当、重复用药、诊断与用药不符、溶媒不当、配伍不当等。结论:本院存在不合理用药现象,医院药学会应加强检查力度及用药指导,临床医师应提高药学知识水平,与药师共同实施防范措施,避免不合理用药,确保临床安全有效、合理用药,不断提高医院合理用药的水平。

Objective:To analyze hospital pharmacy irrational drug use situation,taking intervention measures to improve therational drug use level.Methods:4 586 prescriptions were randomly selected,and the irrational drug use prescriptions were selected.The reasons of irrational drug use were analyzed.The preventive measures were discussed.The rational drug use programs wereformulated.Results:268 cases were irrational drug use prescriptions,the fraction defective was 5.84%. The irrational phenomenonhad undeserved delivery time interval,the abuse of antibiotics,drug improper dosage,undeserved drug use,repeated drug use,diagnosis and drug use discrepancies,improper solvent,improper compatibility and so on.Conclusion:This hospital has irrationaldrug use phenomenon.The hospital medicine institute should strengthen the inspection and medication guidance.The clinicaldoctors should improve the pharmaceutical knowledge level,and combine with pharmacists to implement the preventive measuresto avoid irrational drug use,to ensure the clinical safe and effective,rational drug use,and continuously improve the level of rationaldrug use in hospital.