维持性血液透析患者矿物质和骨异常分析

Analysis of mineral and bone abnormalities in maintenance hemodialysis patients

目的:分析维持性血液透析(MHD)患者矿物质和骨异常现状,探讨高磷血症相关危险因素。方法:收治MHD患者308例,分析血钙、血磷、钙磷浓度乘积及全段甲状旁腺激素(i PTH)达标情况。结果:308例MHD患者透析前血钙、血磷、钙磷乘积及全段甲状旁腺激素达标率分别为62.34%、41.56%、44.16%、24.20%;超重、人血白蛋白升高为高磷血症的独立危险因素,年龄增加是高磷血症的保护因素。结论:本院目前MHD患者血钙、血磷控制并不理想。血磷、i PTH达标率较低,故应加强监测与管理,提高达标率。

Objective:To analyze the status of mineral and bone abnormalities in maintenance hemodialysis(MHD)patients,and to explore the risk factors associated with high phosphorus.Methods:308 maintenance hemodialysis patients were selected.We analyzed the serum calcium,phosphorus,calcium phosphorus product,intact parathyroid hormone(iPTH)standards.Results:The serum calcium,serum phosphorus,calcium phosphorus product and intact parathyroid hormone compliance rate was 62.34% ,41.56%,44.16%,24.20% respectively for 308 cases of MHD patients before dialysis.Overweight and elevated serum albumin were independent risk factors for the high level of phosphorus,and the increased age was the protective factor of the high phosphorus.Conclusion:At present serum calcium and serum phosphorus control of MHD patients in our hospital is not ideal.The serum phosphorus and iPTH compliance rate are low,therefore,monitoring and management should be strengthened to improve the compliance rate.