米非司酮联合米索前列醇终止瘢痕子宫妊娠10～14周的临床疗效

Clinical curative effect of mifepristone combined with misoprostol on the termination of scar uterine pregnancy with 10 to 14 weeks

目的：探讨米非司酮联合米索前列醇终止瘢痕子宫妊娠10～14 周的临床疗效。方法：收治瘢痕子宫妊娠(10～14 孕周)患者204 例为观察组，同期收治非瘢痕子宫妊娠者200 例为对照组。两组患者均选择米非司酮与米索前列醇联合用药方案终止妊娠，对比两组疗效和不良反应。结果：观察组中完全流产195 例，流产成功率95.6%；对照组中完全流产190 例，流产成功率95.0%，两组比较，差异无统计学意义(P＞0.05)。两组不良反应发生率比较，差异无统计学意义(P＞0.05)。结论：米非司酮联合米索前列醇用于终止10～14 周瘢痕子宫妊娠效果确切，流产成功率较高，产程较短，可有效保护子宫，降低手术风险。

Objective:To explore the clinical curative effect of mifepristone combined with misoprostol on the termination of scaruterine pregnancy with 10 to 14 weeks.Methods:204 patients with scar uterine pregnancy(10 to 14 gestational weeks) wereselected as the observation group.At the same time,200 patients with no scar uterine pregnancy were selected as the control group.The two groups all selected mifepristone and misoprostol combined drug scheme on the termination of pregnancy.The curativeeffects and adverse reactions of two groups were compared.Results:In the observation group,195 cases were complete abortion,andthe abortion success rate was 95.6% .In the control group,190 cases were complete abortion,and the abortion success rate was95.0% .The difference between groups was not statistically significant(P>0.05).The incidence rate of adverse reactions werecompared between groups,and the difference was not statistically significant(P>0.05).Conclusion:The mifepristone combinedwith misoprostol on the termination of 10 to 14 weeks scar uterine pregnancy has a exact effect;the abortion success rate is higher;the birth process is shorter.It can effectively protect the uterus and reduce the surgery risk.