孟鲁司特治疗小儿哮喘的临床疗效观察

Observation on the clinical curative effect of montelukast in the treatment of children with asthma

目的:探讨孟鲁司特治疗小儿哮喘的临床疗效。方法:收治哮喘患儿64例,平分为两组,对照组采用常规治疗,观察组在对照组治疗的基础上采用孟鲁司特治疗,对比两组临床疗效。结果:观察组的治疗有效率96.9%,较对照组的78.1%显著提高,差异有统计学意义(P<0.05)。在治疗后,与对照组相比,观察组1 s用力呼气量及最大呼吸流量均显著升高,差异有统计学意义(P<0.05)。结论:孟鲁司特治疗小儿哮喘具有良好效果。

Objective:To investigate the clinical curative effect of montelukast in the treatment of children with asthma.Methods:64 children with asthma were selected.They were divided into the two groups on average.Pateitns in the control group receivedconventional treatment,while patients in the control group were treated with montelukast based on the observation group.Theclinical efficacy of two groups were compared.Results:The effective rate of treatment in the observation group was 96.9%,whichwas significantly higher than that of the control group of 78.1% ,and the difference was statistically significant(P<0.05).Aftertreatment,the 1 second forced expiratory volume and peak flow of the observation group significantly increased compared with thecontrol group,and the difference was statistically significant(P<0.05).Conclusion:Montelukast for the treatment of asthma inchildren has good effect.