小儿支原体肺炎给予莨菪碱注射液及阿奇霉素序贯疗法的临床评价

Clinical evaluation of anisodamine injection and azithromycin sequential in the treatment of mycoplasma pneumonia in children

目的:探讨莨菪碱注射液及阿奇霉素序贯疗法治疗小儿支原体肺炎的效果与安全性。方法:按照双盲随机法将124例支原体肺炎患儿分为对照组和治疗组各62例。两组均贯彻基线治疗方案,对照组在此基础上应用阿奇霉素序贯疗法,对治疗组同时还给予山莨菪碱肺腧穴注射。结果:治疗组治疗总好转率明显高于对照组(P<0.05);治疗组的气促、高热、咳嗽及肺部湿啰音消失时间显著低于对照组(P<0.05)。结论:针对小儿支原体肺炎给予莨菪碱注射液配合阿奇霉素序贯疗法有助于在短时间内改善临床症状,且不良反应少,用药安全性较高。

Objective:To explore the effect and safety of anisodamine injection and azithromycin sequential therapy in thetreatment of children with mycoplasma pneumonia.Methods:According to the double blind randomized method,124 cases ofmycoplasma pneumonia were divided into the control group and the treatment group with 62 cases in each group.Two groups wereimplemented the baseline treatment program,on this basis,the control group used azithromycin sequential therapy,the treatmentgroup at the same time used lung acupoint injection of anisodamine.Results:The total cure rate of the treatment group wassignificantly higher than that of the control group(P<0.05);the shortness of breath,high fever,cough and lung wet ralesdisappearance time of the treatment group was significantly lower than those of the control group(P<0.05).Conclusion:Anisodamine injection combined with azithromycin sequential therapy in the treatment of children with mycoplasma pneumoniacan improve clinical symptoms in a short period of time.Its adverse reactions is less,and the medication safety is high.