摘要
目的:探讨、分析非小细胞肺癌(NSCLC)纵隔淋巴结转移的主要特点。方法:收治NSCLC患者实施肺叶切除联合同侧纵隔淋巴结系统性廓清术治疗的患者132例,重点分析通过病理证实的纵隔淋巴结转移分布情况以及频度。结果:所有患者一共清除了898组纵隔淋巴结,通过手术病理证实256组纵隔淋巴结转移(28.5%)。此次淋巴结共清除1 820枚,通过术后病理证实淋巴结转移522枚(28.7%)。55例患者肿瘤最大直径在3 cm以下,N2淋巴结转移13例(23.6%);77例患者肿瘤最大直径在3 cm以上,N2淋巴结转移30例(39.0%),两组差异存在统计学意义(P<0.05)。低分化N2淋巴结转移率(54.7%)明显高于中分化转移率(25.5%)、高分化转移率(23.1%),差异存在统计学意义(P<0.05)。结论:纵隔淋巴结转移主要集中在上叶癌以上,下叶癌比较多见跨区域转移,纵隔淋巴结转移存在多发性、跨区域性以及跳跃性等特点。
Objective:To investigate the main features of mediastinal lymph nodes metastasis in non-small cell lungcancer(NSCLC).Methods:A total of 132 cases of NSCLC patients treated by pulmonary lobectomy combined with ipsilateralmediastinal lymph node dissection were selected.The distribution and frequency of mediastinal lymph nodes metastasisconfirmed by pathology were analyzed.Results:A total of 898 groups of mediastinal lymph nodes were removed,and 256mediastinal lymph nodes were confirmed by operation and pathology(28.5%).The lymph nodes were removed 1 820,and 522 wereconfirmed by postoperative pathological lymph node metastasis (28.7%).The maximum diameter of the tumor was less than 3 cmin 55 cases,N2 lymph node metastasis in 13 cases(23.6%).The maximum diameter of the tumor was more than 3 cm in 77 cases,N2 lymph node metastasis in 30 cases(39%),and there was statistical significance in the difference between groups(P<0.05).Therate of lymph node metastasis of poorly differentiated N2(54.7%)was significantly higher than that of middle differentiation(25.5%)and high differentiation(23.1% ),and the difference was statistically significant(P<0.05).Conclusion:Mediastinal lymph nodemetastasis is mainly concentrated in the upper lobe cancer,and lower lobe cancer is more common with cross regional transfer.There are many characteristics of mediastinal lymph node metastasis,such as multiple,trans regional and jumping.
作者
吉红波
Ji Hongbo(Department of Cardiothoracic Surgery,the First People's Hospital of Qujing City,Yunnan Province 655009)
出处
《中国社区医师》
2016年第13期77-78,共2页
Chinese Community Doctors
关键词
非小细胞肺癌
淋巴结转移
主要特点
Non small cell lung cancer
Lymph node metastasis
Main characteristics