胱抑素C、肌酐、尿素氮在肾病中的诊断价值

The value of cystatin C,creatinine and urea nitrogen in the diagnosis of kidney disease

目的:探讨胱抑素C(Cys-C)、肌酐(CREA)和尿素氮(BUN)在肾脏损害中的诊断价值。方法:收治肾病患者121例,进行Cys-C、CREA和BUN检测。结果:肾病患者在肾功能损伤程度不同时所测Cys-C、CREA和BUN的结果与健康对照组比较,差异具有统计学意义(P<0.05)。结论:肾功能轻度损伤时Cys-C浓度显著升高,与CREA和BUN同时检测有助于肾脏病变的早期诊断和疗效检测。

Objective:To investigate the value of serum cystatin C(Cys-C),creatinine(CREA)and urea nitrogen(BUN)in thediagnosis of renal injury.Methods:121 patients with renal disease were selectd.Cys-C,CREA and BUN were detected in allpatients.Results:The results of BUN,CREA and Cys-C in patients with different degree of renal function injury were significantlydifferent from those in the healthy control group (P<0.05).Conclusion:The Cys-C concentration was significantly increased in therenal function with mild impairment,and the detection of CREA and BUN simultaneously was helpful for early diagnosis andtreatment of renal disease.