临床抗生素应用与细菌耐药性分析

Clinical application of antibiotics and analysis of bacterial drug resistance

目的:探讨抗生素的应用情况及细菌耐药性情况。方法:收治感染患者125例,分析抗生素的种类、使用情况以及不同菌种对抗生素的耐药情况。结果:抗生素使用率96.0%,头孢菌素类所占比例最高(96.7%);抗生素平均使用时间(23.21±2.52)d;联合用药率53.3%;革兰阴性、阳性菌耐药性主要体现在青霉素类、头孢类抗生素。结论:临床医师应充分结合细菌耐药情况,合理使用抗生素,保障用药安全。

Objective:To investigate the application of antibiotics and the drug resistance of bacteria.Methods:125 patients withinfection were selected,and we analyzed the types and usage of antibiotics and the resistance of different strains to antibiotics.Results:The probability of using antibiotics was 96% ,and the highest proportion was cephalosporins accounted for 96.7% .Theaverage use time of antibiotics was(23.21±2.52)d.The combined drug use rate was 53.3%.The drug resistance of gram negativeand positive bacteria was mainly reflected in the penicillins and cephalosporins.Conclusion:Clinicians should fully consider thebacterial drug resistance,use antibiotics reasonably and ensure the safety of drug use.