急性脑梗死老龄人群给予超选择性动脉溶栓对比静脉溶栓的临床研究

Clinical study of super selective artery thrombolysis and intravenous thrombolysis in the treatment of elderly patients with acute cerebral infarction

目的:探讨急性脑梗死老龄人群给予超选择性动脉溶栓对比静脉溶栓的临床效果。方法:研究组实施超选择性动脉溶栓,对照组实施静脉溶栓,比较两组的治疗效果。结果:两组NIHSS评分和BI评分随时间逐渐降低,但组间同时段对比,差异无统计学意义(P>0.05)。研究组总再通率84.09%,显著优于对照组的59.09%。两组不良反应发生率比较,差异无统计学意义(P>0.05)。结论:急性脑梗死老龄人群给予超选择性动脉溶栓与静脉溶栓治疗其近期和远期疗效均显著,安全性好,但需严格把控时间窗。

Objective:To explore the clinical effect of super selective artery thrombolysis and intravenous thrombolysis in thetreatment of elderly patients with acute cerebral infarction.Methods:The study group was given super selective artery thrombolysis.The control group was given intravenous thrombolysis.We compared the treatment effect of the two groups.Results:The NIHSSscores and BI scores of the two groups were gradually decreased with time,but there was no significant difference between groupsat the same time.In the study group,the total recanalization rate of 84.09% was significantly better than 59.09% of the controlgroup.There was no significant difference in the incidence of adverse reactions between the two groups.Conclusion:The short andlong term effects of super selective artery thrombolysis and intravenous thrombolysis in the treatment of elderly patients with acutecerebral infarction were significant,and the security was good,but we need to strictly control the time window.