静脉滴注加雾化吸入盐酸氨溴索治疗新生儿呼吸窘迫综合征的临床疗效及体会

Clinical curative effect experience of intravenous infusion and inhalation of ambroxol hydrochloride in the treatment of neonatal respiratory distress syndrome

目的:探讨静脉滴注加雾化吸入盐酸氨溴索治疗新生儿呼吸窘迫综合征的临床治疗效果。方法:收治呼吸窘迫综合征新生儿60例,分为两组,对照组给予雾化吸入盐酸氨溴索治疗,观察组在此基础上加用静脉滴注盐酸氨溴索治疗,比较两组新生儿有效率。结果:观察组新生儿的治疗有效率达90.0%,明显高于对照组的70.0%,差异有统计学意义(P<0.05);治疗组PaO_2改善明显优于对照组,差异具有统计学意义(P<0.05)。结论:在新生儿呼吸窘迫综合征的临床治疗上,静脉滴注加雾化吸入盐酸氨溴索的治疗效果显著。

Objective:To explore the clinical curative effect of intravenous infusion and inhalation of ambroxol hydrochloride inthe treatment of neonatal respiratory distress syndrome.Methods:60 patients with neonatal respiratory distress syndrome wereselected.They were divided into the two groups.The control group was given inhalation of ambroxol hydrochloride,and theobservation group was treated with intravenous injection of ambroxol hydrochloride on the basis of the control group.We comparedthe efficiency of neonates in the two groups.Results:The treatment effective rate in the observation group was 90%,significantlyhigher than that in the control group of 70% ,with significant statistically difference(P<0.05).The improvement of PaO2 in thetreatment group was significantly better than that in the control group,and the difference was statistically significant(P<0.05).Conclusion:In the clinical treatment of neonatal respiratory distress syndrome,intravenous infusion and inhalation of ambroxolhydrochloride can get significant effect.