单唾液酸神经节苷脂钠联合新生儿抚触疗法在新生儿缺氧缺血性脑病治疗中的价值研究

The value of monosialotetrahexosyl ganglioside sodium combined with neonatal massage therapy in the treatment of neonatal hypoxic ischemic encephalopathy

目的:探讨单唾液酸神经节苷脂钠联合新生儿抚触疗法治疗新生儿缺氧缺血性脑病的效果。方法:收治新生儿缺氧缺血性脑病患儿258例,按照随机双盲的方式分成观察组和对照组各129例。对观察组和对照组均给予常规治疗,观察组在此基础上通过神经节苷脂钠、新生儿抚触疗法治疗。结果:观察组治疗总有效率高于对照组(P<0.05)。结论:新生儿缺氧缺血性脑病采取单唾液酸神经节苷脂钠联合新生儿抚触疗法治疗,可促使新生儿受损神经及早得以恢复,并降低神经功能性障碍。

Objective:To investigate the effect of monosialoganglioside injection combined with neonatal massage therapy in thetreatment of neonatal hypoxic ischemic encephalopathy.Methods:258 children with neonates hypoxic ischemic encephalopathywere selected.They were divided into the observation group and the control group according to the random double blind way with129 cases in each.Patients in the observation group and the control group were given the conventional treatment,and theobservation group were given the ganglioside sodium, newborn massage therapy on the basis of this.Results:The total effective rateof the observation group was higher than that of the control group(P<0.05).Conclusion:Single sialic acid ganglioside sodiumcombined with neonatal massage therapy in the treatment of neonatal hypoxic ischemic encephalopathy can prompt the neonatalnerve damage as soon as possible to recover,and reduce the nerve function disorder.