消化性溃疡合并上消化道出血的治疗效果分析

Analysis of therapeutic effect of peptic ulcer complicated with upper gastrointestinal bleeding

目的:探讨消化性溃疡合并上消化道出血的最有效治疗方式。方法:收治消化性溃疡合并上消化道出血患者80例,随机分为观察组和对照组各40例,观察组采用奥美拉唑+克拉霉素+阿莫西林治疗,对照组采用雷尼替丁+甲硝唑+阿莫西林治疗,比较两组的治疗效果。结果:观察组总有效率97.50%,明显高于对照组的82.50%(P<0.05)。治疗后,空腹胃液p H值都有所上升,但观察组的上升效果更明显(P<0.05)。结论:采用奥美拉唑+克拉霉素+阿莫西林治疗消化性溃疡合并上消化道出血效果显著。

Objective:To explore the most effective treatment of peptic ulcer complicated with upper gastrointestinal bleeding.Methods:80 patients with peptic ulcer complicated with upper gastrointestinal bleeding were selected.They were randomly divided into the observation group and the control group with 40 cases in each group.The patients in the observation group were treated with omeprazole and clarithromycin and amoxicillin.The patients in the control group were treated with ranitidine and metronidazole and amoxicillin.We compared the therapeutic effect of two groups.Results:The total effective rate of the observation group of 97.50% was significantly higher than 82.50% of the control group(P < 0.05).After treatment,the fasting gastric juice pH value was increased,but the effect of the observation group was more obvious(P < 0.05).Conclusion:The therapeutic effect of omeprazole plus clarithromycin plus amoxicillin in the treatment of peptic ulcer complicated with upper gastrointestinal bleeding was significant.