难治性胃食管反流病72例的原因及治疗分析

Discussion on the reason and treatment of 72 patients with refractory gastroesophageal reflux disease

目的:探讨难治性胃食管反流病(RGERD)病因和治疗措施。方法:回顾性分析确诊的RGERD患者的诊断措施及治疗方法及效果。结果:以不恰当的生活方式和饮食为主要病因的9例,不按医嘱服药的7例,食管动力障碍为主的5例,胃酸反流为主的32例,高敏感性食管11例,胆汁反流4例。72例患者中,患者症状缓解59例,明显缓解13例。结论:RGERD病因多样,以泮托拉唑为基础用药,强调针对不同病因的个体化治疗效果良好。

Objective:To investigate the etiology and treatment of refractory gastroesophageal reflux disease(RGERD).Methods:The diagnostic measures,treatment methods and therapeutic effects of the patients who diagnosed with RGERD were retrospectively analyzed.Results:9 cases of patients with inappropriate lifestyle and diet as the main cause of disease;7 patients did not follow the prescribed medicine;esophageal motility disorders in 5 cases;gastric acid reflux in 32 cases;11 cases of esophageal hypersensitivity;bile reflux in 4 cases.In 72 patients,59 cases were relieved and 13 cases were obviously relieved.Conclusion:The etiology of RGERD and is diversity;with pantoprazole based medicine and emphasizes the individualized treatment according to different causes;the effect is good.