婴儿肝炎综合征中巨细胞病毒感染率分析

Infection rate analysis of cytomegalovirus infection in infantile hepatitis syndrome

目的:探讨婴儿肝炎综合征中巨细胞病毒的感染率。方法:收治肝炎综合征婴儿60例,行肝功能检查、TORCH病原学检查(血清ELISA检测CMV-Ig M)、血CMV-DNA、代谢病筛查和影像学检查,观察病毒血清学检测结果和血CMV-DNA检测结果,总结巨细胞病毒感染率。结果:在60例患儿中,乙肝病毒感染2例,CMV-Ig M阳性22例(36.7%),血CMV-DNA阳性19例(31.7%),表明巨细胞病毒感染率约31.7%。结论:巨细胞病毒是婴儿肝炎综合征中的重要病原体,应当及早发现巨细胞病毒感染者,对其进行必要的隔离,并采取适当治疗和护理措施,降低并发症发生率和改善预后。

Objective:To explore the infection rate of cytomegalovirus infection in infantile hepatitis syndrome.Methods:60 cases with infant hepatitis syndrome were selected.They were given liver function examination,TORCH etiological examination(serum ELISA examination for CMV-IgM),blood CMV-DNA,metabolic disease screening and imaging examination.We observed virus serological test results and blood CMV-DNA detection results,and summarized the rate of cytomegalovirus infection.Results:In 60 cases,2 cases had hepatitis B virus infection;22 cases(36.7%) had positive CMVIgM;19 cases(31.7%) had positive blood CMV-DNA,which indicated that the cytomegalovirus infection rate was about 31.7%.Conclusion:Cytomegalovirus was an important pathogen in infantile hepatitis syndrome.We should make early detection of cytomegalovirus infection,and take the necessary isolation and appropriate treatment and nursing measures,so as to reduce the incidence of complications and improve the prognosis.