肺心病血栓前状态及抗凝干预疗效

Study on pre-thrombus state of pulmonary heart disease and the effect of anticoagulation

目的:探讨肺心病血栓前状态及抗凝干预疗效。方法:收治肺心病患者100例,按照数字表法随机分为试验组与常规组各50例。常规组采用常规治疗,试验组加强抗凝干预治疗。结果:试验组血浆凝血酶片段、纤维蛋白原、D-二聚体明显低于常规组(P<0.05);试验组PaCO_2、PaO_2、总效率明显优于常规组(P<0.05)。结论:对肺心病患者加强抗凝干预治疗能有效恢复患者的凝血参数,改善患者的血气指标,提高患者的治疗有效率。

Objective:To investigate the pre-thrombus state of pulmonary heart disease and the effect of anticoagulation.Methods:100 patients with pulmonary heart disease were randomly divided into the experimental group and the conventionalgroup with 50 cases in each group.Patients in the conventional group were treated with routine treatment,while in theexperimental group were treated with anticoagulant therapy.Results:The levels of thrombin,fibrinogen and D-dimer inthe experimental group were significantly lower than those in the conventional group(P < 0.05);the PaCO2,PaO2 andthe total efficiency of the experimental group were significantly better than those of the conventional group(P < 0.05).Conclusion:Strengthening anticoagulation therapy on patients with pulmonary heart disease can restore the coagulationparameters effectively,improve the patients blood gas index,and increase the efficiency of treatment.