规范化二级预防对老年冠状动脉粥样硬化患者的近远期疗效观察

Observation on short and long-term effects of standardized secondary prevention on coronary atherosclerosis in elderly patients

目的:研究规范化二级预防对老年冠状动脉粥样硬化患者的近远期疗效。方法:收治老年冠状动脉粥样硬化患者102例,随机分为对照组和观察组各51例。对照组给予常规抗血小板聚集、活血化瘀等药物治疗,观察组在对照组基础上给予规范化二级预防。结果:治疗4周后,观察组血清总胆固醇、血清甘油三酯明显低于对照组(P<0.05);观察组远期治疗有效率、生存质量评分明显高于对照组(P<0.05)。结论:规范化二级预防在早期能有效改善降血脂疗效,从长远角度看,能显著稳定和恢复患者的健康,改善预后和提高生活质量。

Objective:To study the short and long-term effects of standardized secondary prevention on elderly patients with coronary atherosclerosis.Methods:102 elderly patients with coronary atherosclerosis were randomly divided into the control group and the observation group,with 51 cases in each group.The control group received conventional anti platelet aggregation,blood circulation and other drug treatment,while the observation group received standardized secondary prevention on the basis of the treatment taken by the control group.Results:After 4 weeks of treatment,the serum total cholesterol and serum triglyceride in the observation group were significantly lower than those in the control group(P<0.05);the long-term treatment efficiency of the observation group was significantly higher than the control group(P<0.05).Conclusion:Standardized secondary prevention can improve the efficacy of lowering blood lipid effectively in early period.It can significantly stabilize and recover the patient's condition,and improve the prognosis and the quality of life in the long run.