血清CEA和CA-199水平变化在结直肠癌根治术后局部复发中的临床价值研究

Clinical value of changes of serum CEA and CA-199 levels in patients with local recurrence after radical resection of colorectal cancer

目的:探讨血清CEA及CA-199水平在结直肠癌根治术后局部复发中的临床意义。方法:收治结直肠癌根治术患者410例,检测CEA和CA-199水平,分析其与局部复发的关系。结果:在复发患者中,血清CEA和CA-199水平明显高于未复发患者(P<0.05)。结论:监测结直肠癌术前、术后CEA、CA-199水平,对判断结直肠癌根治术后局部复发有重要意义。

Objective:To explore the clinical value of changes of serum CEA and CA-199 levels in patients with local recurrenceafter radical resection of colorectal cancer.Methods:410 patients with radical resection of colorectal cancer were selected,CEA andCA-199 levels were detected,and we analyzed their relationship with local recurrence.Results:In patients with recurrence,serumCEA and CA-199 levels were significantly higher than those of patients without recurrence(P<0.05).Conclusion:Monitoringpreoperative and postoperative CEA and CA-199 levels had important significance to judge the local recurrence after radicalresection of colorectal cancer.